https://basulabnyc.org/publications daily 0.75 2024-12-16 https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/5d876ba9-29a8-4704-8ea0-0b8a38aa4887/Nature+Reviews+Cover.png Publications - Make it stand out Regulation of long non-coding RNAs and genome dynamics by the RNA surveillance machinery https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/f14c76c9-7038-4286-ad0f-1ffad74ae379/Science+Immunology+Cover.png Publications - Make it stand out RNA exosome drives early B cell development via noncoding RNA processing mechanisms https://images.squarespace-cdn.com/content/v1/5ce435d6bea1ed00016ba287/1558964652247-5MWXNMFZVOPGE4TY6U2Q/MHeiderich_ReflexionenZwei-05-copy.jpg Publications https://basulabnyc.org/people daily 0.75 2024-12-19 https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1605221823010-SWW1GCDVR8ZQ8H11LSZ0/IMG_2923.jpg People Professor of Microbiology and Immunology https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1627998077345-QX9YTYSWIDS6835G9B68/IMG-3875.jpg People Postdoctoral Research Scientist https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1606762760677-A92CL8V8CSJ1QRL0FHG1/IMG-3141.jpg People Postdoctoral Research Scientist https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/44f3fe55-59a3-4a7f-901b-f9035a4e3dd6/shareImage_1734375325.jpg People Postdoctoral Research Scientist https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1605225132994-OCMEMLJF517V8KGXEXOY/IMG_3131.JPG People - Make it stand out Associate Research Scientist https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1605224932589-H3X7HXFBJHH4RJV0T0LA/IMG_3002.jpg People Associate Research Scientist https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1604237371805-GI7DKOPSI5C4XUHBCNS6/IMG_2539.jpg People Staff Research Scientist https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/ff1e060e-20cb-4932-adfb-480850d36300/Max+Headshot.png People MD/PhD candidate https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/da401fba-fce8-402f-8e54-aa138abbd736/Eric+Headshot.jpg People - Make it stand out PhD candidate https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/c5ade58d-228a-4a61-953d-824fc9140f52/IMG_5654.jpg People PhD candidate https://basulabnyc.org/lab-events daily 0.75 2022-06-15 https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1630350792538-SZW4DKMJ7R43RGHL8WKD/Screen+Shot+2021-08-30+at+3.04.59+PM.png Lab Events Check out our latest research, published in Molecular Cell! https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1628633460975-ZWCS9RG5ZWR9AINVWFFA/unnamed.jpg Lab Events https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/3c309389-44c4-4ecc-826f-ae574dcafecc/max+headshot.jpg Lab Events - Make it stand out Max got his crossword puzzles published in the New York Times! Congrats Max! https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/08546281-b10f-4c49-8ed0-b7184c49d865/Science+Immunology+Cover.png Lab Events - Make it stand out Front cover! (click here for article) https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1630350422027-L1QMMCW63MBCNKE6ANBW/Screen+Shot+2021-08-30+at+3.04.38+PM.png Lab Events Dressing up Noncoding RNA to Dress Down Infections (click for full article!) https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1627999814861-CY56GKHI7PE3ITTQ3RL3/IMG-4387.JPG Lab Events Welcome to Jerson! Jerson Estrella has joined the lab as a PhD student this summer. He has earned his bachelor’s degree in Microbiology and Immunology at University of California, Irvine. In grad school he’s interested in identifying noncoding regions of the genome that might have important regulatory function in elaborating cell immune-responses. August 2nd, 2021 https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1627999505776-PO9PVT9Z0QFBEQ74WUI3/IMG_3943.jpg Lab Events https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1619909349253-WHL1B8S4GE9UGUVPHO70/PHOTO-2021-05-01-17-31-17.jpg Lab Events Way to go, Kishore! Kishore has done a great job on presenting his postdoctoral project and research interests to the M&I Research in Progress seminar series! April 30, 2021 https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1619910118162-2YMYUIOJZVNMRPHCVJEN/IMG_1742.jpg Lab Events https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1619036860902-SZPTV642NTML0FN22IRC/IMG_1428.jpg Lab Events https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1617828598724-14YMPMOURW2COFG3V90T/71181020-CCE0-4C7B-B0E1-53AA2A767DAE.JPG Lab Events Warm welcome to the new lab member: Toro Rothschild! Featuring: Gerson and Toro in their way to develop a terrific western blot! April 7, 2021 https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1617749141656-ODEBTLYQYA9GLYZADB0B/Lab_Meeting.jpg Lab Events Lab Meeting April 6th 2021! Presenters: Mukesh & Wanwei April 6, 2021 https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1612284229575-CAJ06UYQY6CKMUXZDI84/Screen-Shot-2021-02-02-at-11.40.45-AM.png Lab Events https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1612284295338-9TLXTKIAAXBRO66JVCNF/site2.png Lab Events https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1605230671839-JPC5ASXLWGWTXRD0WONI/IMG_1730.jpg Lab Events https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1605231084033-WHULQ7TNW35I05UGP5QN/IMG_2122.jpg Lab Events https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1605230756562-B3KTTBAT7Y8ZYRE0OQSG/Image.jpeg Lab Events https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1627999755214-XM5BQYAYGZAATG7256X4/IMG_1658.jpg Lab Events Au Revoir, Brice! September 1st 2020 https://basulabnyc.org/funding daily 0.75 2020-12-07 https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1606958068979-G5M2DXUQ05RIJYX0TY76/LLSC12.png Funding https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1606958728567-4X2TO41NFP04BIR7MYBT/NIH_Master_Logo_Vertical_2Color.png__23226.png Funding https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1606958100419-HROVRT14D3SZEZ2V4F28/LRF_logo_RGB.png Funding https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1607350628858-JL9YOUC70V1RRB8OIOJS/Pershing+Square.jpeg Funding https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1607350553946-KXFDOZ21A37M4X0NUZ1V/embo_lores.png Funding https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1606958748972-0KP3L5ZCGQERLJYHYN56/NIH_Master_Logo_Vertical_2Color.png__23226.png Funding https://basulabnyc.org/contact daily 0.75 2024-12-16 https://basulabnyc.org/research daily 0.75 2024-12-18 https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1605235027786-O430631O9D489R9MV5IR/Screen+Shot+2020-11-12+at+9.31.27+PM.png Research RNA processing https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/552a7aab-6e67-4f8d-91f3-fcb4f23c6df5/Translocation+fig+copy.jpg Research - Make it stand out Somatic Hypermutation https://basulabnyc.org/home daily 1.0 2022-06-15 https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/1606960660693-PGLO0X0QAD5L6PX3KM0X/image-asset.jpeg Research The department of Microbiology and Immunology The Basu Lab is part of the Department of Microbiology & Immunology, in the Vagelos College of Physicians and Surgeons at Columbia University Irving Medical Center. We are members of the Graduate School of Arts and Sciences of Columbia University. Our Department offers a Graduate Training Program in Microbiology, Immunology and Infection. https://images.squarespace-cdn.com/content/v1/5f8f5dd98b002011347c2d14/738beefa-ea0b-4dd3-b046-a576cd91edab/Science+Immunology+Cover.png Research - Mechanisms that control DNA and RNA diversity in mammalian cells DNA mutations and noncoding RNA expression can be both useful and detrimental to cells. Although somatically induced DNA alterations are important for B and T cell development, they are widely seen as drivers of various malignancies. Similarly, RNA expression both from coding and noncoding regions of the genome needs to be controlled by post transcriptional processing to prevent adverse effects including onset of RNA induced genomic instability, RNA interference, altered control of DNA regulatory elements, or activation of RNA induced inflammatory responses.